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Nitrogen mustard compounds

Nitrogen mustards are cytotoxic organic compounds with the chloroethylamine functional group, which consists of the following structure: Cl(CH2)2NR2, where R can be any organic group. They are nitrogen analogs of mustard gas.
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Keyword Search:
136 – 150 of 175 results
136

Medchemexpress LLC N-Methylmoranoline | 69567-10-8 | 177.20 | 10 MG
SDP

N-Methylmoranoline is an alpha-glucosidase inhibitor. It appears as a white to off-white solid.

  • Functions as an alpha-glucosidase inhibitor
  • Suitable as a reference compound
  • Powder stable for 3 years at -20°C
  • In solvent stable for 6 months at -80°C, or 1 month at -20°C

ENCOMPASS_PREFERRED
137

eMolecules​ 19853-10-2 | 2-([1,1'-BIPHENYL]-2-YL)ACETONITRILE | AstaTech | MFCD00060294 | 193.249 | C14H11N | 98.000 | N#CCc1ccccc1-c1ccccc1 | 1g | 493153604

2-([1,1'-BIPHENYL]-2-YL)ACETONITRILE | AstaTech | 19853-10-2 | MFCD00060294 | 193.249 | C14H11N | 98.000 | N#CCc1ccccc1-c1ccccc1 | 1g | 493153604

ENCOMPASS_PREFERRED
138

Medchemexpress LLC Gamcemetinib | 1887069-10-4 | 99.1% | C22H20ClN5O3S | 10MG
SDP

Gamcemetinib is a covalent, irreversible inhibitor of MAP kinase-activated protein kinase-2 (MK2) used as a research compound for in vitro and preclinical studies. It is characterized by submicromolar activity in biochemical and cell-based assays and is supplied as a solid or as a DMSO solution for laboratory use.

  • Potent, covalent MK2 inhibitor with low-nanomolar to submicromolar activity.
  • High purity suitable for research use (≈99.1%).
  • Available as multiple solid quantities and as a 10 mM solution in DMSO for convenience.
  • Soluble in DMSO; enhanced solubility with warming and sonication.
  • Defined storage recommendations for powder and solution to preserve stability.

ENCOMPASS_PREFERRED
139

Medchemexpress LLC 2-phenylaminoadenosine | 53296-10-9 | MFCD00055119 | 98.0% | 358.35 g/mol | C16H18N6O4 | 5 MG
SDP

CV1808 (2-phenylaminoadenosine) is a research-grade, non-selective A2 adenosine receptor agonist used in pharmacology and receptor-binding studies. It shows reported Ki values of 76 nM at the A2A receptor and 1,450 nM at the A3 receptor, has molecular formula C16H18N6O4 and molecular weight 358.35 g/mol, and is supplied as a solid with analytical purity around 98.0% for research use only.

  • Non-selective A2 adenosine receptor agonist
  • Reported Ki: A2A = 76 nM; A3 = 1,450 nM
  • Molecular formula C16H18N6O4; molecular weight 358.35 g/mol
  • Analytical purity approximately 98.0%
  • Supplied as a solid for laboratory research applications

ENCOMPASS_PREFERRED
140

Medchemexpress LLC Ascr#18 | 1355681-10-5 | 5 MG
SDP

Ascr#18 is an ascaroside that functions as a hormone in nematodes and is expressed during nematode development. It enhances resistance in various plants such as Arabidopsis, tomato, potato, and barley against viral, bacterial, oomycete, fungal, and nematode infections.

  • Functions as a hormone in nematodes
  • Expressed during nematode development
  • Enhances resistance in various plants (Arabidopsis, tomato, potato, barley)
  • Provides resistance against viral, bacterial, oomycete, fungal, and nematode infections
  • Improves pathogen resistance and activates defense responses in Arabidopsis (in vitro studies)

ENCOMPASS_PREFERRED
141

Medchemexpress LLC Camonsertib | 2417489-10-0 | 99.99% | 410.47 | 50 MG
SDP

Camonsertib is an orally active, selective ATR kinase inhibitor (ATRi) with an IC50 of 1.00 nM in biochemical assays. It demonstrates 30-fold selectivity for ATR over mTOR and over 2,000-fold selectivity over ATM, DNA-PK, and PI3Kα kinases, exhibiting potent antitumor activity.

  • Orally active, selective ATR kinase inhibitor (ATRi) with an IC50 of 1.00 nM.
  • Demonstrates 30-fold selectivity for ATR over mTOR.
  • Exhibits potent antitumor activity.
  • Inhibits CHK1(Ser345) phosphorylation in LoVo cells.
  • Produces dose-dependent tumor growth inhibition in xenografts.
  • Shows greater anti-tumor effects in combination with PARPi Olaparib.

ENCOMPASS_PREFERRED
142

Medchemexpress LLC Toringin | 1329-10-8 | 99.6% | 416.38 g/mol | C21H20O9 | 10 MG
SDP

Toringin is a natural bioflavonoid isolated from the bark of Docyniopsis tschonoski, supplied for research use as a white-to-yellow solid (CAS 1329-10-8). The compound is offered in small research pack sizes and is accompanied by a product data sheet and safety data sheet.

  • Natural bioflavonoid isolated from Docyniopsis tschonoski.
  • White to yellow solid suitable for analytical and biological research.
  • Reported high purity (approximately 99.6%).
  • Supplied as a 10 mg vial for small-scale experiments.
  • Documentation available: product data sheet and safety data sheet.
  • Recommended storage: powder at -20°C; in solvent, -80°C for long-term storage.

ENCOMPASS_PREFERRED
143

Medchemexpress LLC Cdc25b-in-1 | 2374831-10-2 | 98.1% | 321.37 g/mol | C20H19NO3 | 10MG
SDP

CDC25B-IN-1 is a small-molecule research inhibitor of the cell division cycle 25B (CDC25B) phosphatase, referred to in the literature as compound 4a. It is provided as a 10 mg research sample (CAS 2374831-10-2) for biochemical and cellular studies targeting CDC25B-mediated signaling.

  • Potent CDC25B inhibition with reported Ki of 8.5 μM.
  • High purity suitable for research (≈98.1%).
  • Molecular weight 321.37 g/mol; formula C20H19NO3.
  • Suitable for in vitro biochemical and cell-based assays.
  • Storage under nitrogen recommended; refrigerated at 4°C; in solvent: -80°C (6 months) or -20°C (1 month).
  • Supplied as a small quantity research sample for laboratory use.

ENCOMPASS_PREFERRED
144

Medchemexpress LLC Toringin | 1329-10-8 | 5 MG
SDP

Toringin is a bioflavonoid isolated from the bark of Docyniopsis tschonoski. It decreases the cis-effect of expanded CTG repeats and cytotoxicity, and rescues PC12 neuronal cells when exposed to isosakuranetin. As a flavonoid, Toringin exhibits various biological activities beneficial against conditions such as cancers and coronary heart disease, and is effective in ameliorating RNA gain of function caused by expanded CTG repeats.

  • Decreases cis-effect of expanded CTG repeats
  • Decreases cytotoxicity
  • Rescues PC12 neuronal cells
  • Ameliorates RNA gain of function
  • Exhibits various biological activities
  • Beneficial against cancers and coronary heart disease

ENCOMPASS_PREFERRED
145

STA PHARMACEUTICAL US LLC 3-(9-fluorenylmethoxycarbonylamido)-tricyclo[3.3.1.1(3.7)]decane-1-carboxylic acid | 5 g | CAS 875211-10-2 | InChIKey RXRDRSUDCSEVRK-UHFFFAOYSA-N

3-(9-fluorenylmethoxycarbonylamido)-tricyclo[3.3.1.1(3.7)]decane-1-carboxylic acid is a Amino Acid reagent (Subcategory: Alkane AA) sold by WuXi TIDES. Offered in 5 g. Store at 4 °C. SDS available for reference.

Specifications
- CAS: 875211-10-2
- MDL: No data
- InChIKey: RXRDRSUDCSEVRK-UHFFFAOYSA-N
- Molecular Weight: 417.505
- Molecular Formula: C26H27NO4
- Purity: ≥95%
- Container Type: 30 mL HDPE
- Pack Size: 5 g
- Net Weight: 5 g
- Gross Weight: 16.5 g
- Commodity Code: 29242970
- Country Of Origin: China
- IUPAC: 3-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)adamantane-1-carboxylic acid
- SMILES: OC(C12CC3CC(C2)CC(C1)(NC(OCC4C5=CC=CC=C5C6=CC=CC=C46)=O)C3)=O

ENCOMPASS
146

eMolecules​ 471254-10-1 | 3-PYRROLIDINECARBOXAMIDE | AstaTech | MFCD09037932 | 114.148 | C5H10N2O | 95.000 | NC(=O)C1CCNC1 | 0.1g | 718055558

3-PYRROLIDINECARBOXAMIDE | AstaTech | 471254-10-1 | MFCD09037932 | 114.148 | C5H10N2O | 95.000 | NC(=O)C1CCNC1 | 0.1g | 718055558

ENCOMPASS_PREFERRED
147

Medchemexpress LLC 2-chloroethyl (2-chloroethyl)phosphonate | 17378-30-2 | MFCD24393365 | >95.0% | 206.99 | C4H9Cl2O3P | 10 MG
SDP

2-Chloroethyl (2-chloroethyl)phosphonate is an organophosphorus compound used as an intermediate in organic synthesis. The compound is identified by CAS 17378-30-2 and is characterized by the molecular formula C4H9Cl2O3P and a molecular weight of 206.99 g/mol (manufacturer datasheet).

  • Used as a building block or intermediate in organic synthesis.
  • Organophosphorus chemical class with a phosphoryl functionality.
  • CAS number 17378-30-2 for unambiguous identification.
  • Molecular formula C4H9Cl2O3P, molecular weight 206.99 g/mol.
  • Reported purity >95% (HPLC) from analytical standards vendors.
  • Available in small laboratory quantities suitable for research use.

ENCOMPASS_PREFERRED
148

Medchemexpress LLC MS4077 | 2230077-10-6 | 99.7% | 1134.73 | 10 MG
SDP

MS4077 is an anaplastic lymphoma kinase (ALK) PROTAC (degrader) based on Cereblon ligand, with a Kd of 37 nM for binding affinity to ALK. It is for research use only and not sold to patients.

  • Effectively inhibits cancer cell proliferation.
  • Concentration-dependently inhibits proliferation of SU-DHL-1 cells with an IC50 of 46 ± 4 nM.
  • Potently reduces ALK fusion protein levels and inhibits ALK auto-phosphorylation and downstream STAT3 phosphorylation in SU-DHL-1 and NCI-H2228 cells.
  • Reduces NPM-ALK protein levels with a DC50 of 3 ± 1 nM in SU-DHL-1 cells after 16-hour treatment.
  • Achieves over 90% inhibition of both ALK Y1507 and STAT3 Y705 phosphorylation at 100 nM concentration.
  • Reduces EML4-ALK protein levels with a DC50 of 34 ± 9 nM in NCI-H2228 cells after 16-hour treatment, with over 90% reduction at 100 nM.

ENCOMPASS_PREFERRED
149

eMolecules​ 1122-69-6 | 2-ETHYL-6-METHYLPYRIDINE | AstaTech | MFCD00023531 | 121.183 | C8H11N | 97.000 | CCc1cccc(C)n1 | 0.25g | 721956956

2-ETHYL-6-METHYLPYRIDINE | AstaTech | 1122-69-6 | MFCD00023531 | 121.183 | C8H11N | 97.000 | CCc1cccc(C)n1 | 0.25g | 721956956

ENCOMPASS_PREFERRED
150

Chemscene ChemScene | 6-Bromopyrazolo[1,5-a]pyrimidine | 10G | CS-M2471 | 0.98 | 705263-10-1| MFCD09832894 | 198.023
SDP

ChemScene | 6-Bromopyrazolo[1,5-a]pyrimidine | 10G | CS-M2471 | 0.98 | 705263-10-1| MFCD09832894 | 198.023

ENCOMPASS_PREFERRED