Nitrogen mustard compounds
Medchemexpress LLC HN37 | 1821222-10-9 | 99.5% | C20H21FN2O2 | 100 MG
HN37 is a potent and chemically stable antiepileptic agent candidate, demonstrating an EC50 of 37 nM for KCNQ2. It functions as a click chemistry reagent, containing an Alkyne group that enables it to undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules possessing Azide groups. It is also recognized as a potent neuronal Kv7 activator, exhibiting subtype selectivity similar to RTG.
- Potent and chemically stable antiepileptic agent candidate
- Functions as a click chemistry reagent
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide groups
- Potent neuronal Kv7 activator
- Exhibits subtype selectivity similar to RTG
- Molecular weight of 340.39
- Appears as an off-white to light yellow solid
- Intended for research use only
Medchemexpress LLC N-Methylmoranoline | 69567-10-8 | 177.20 | 10 MG
N-Methylmoranoline is an alpha-glucosidase inhibitor. It appears as a white to off-white solid.
- Functions as an alpha-glucosidase inhibitor
- Suitable as a reference compound
- Powder stable for 3 years at -20°C
- In solvent stable for 6 months at -80°C, or 1 month at -20°C
Aobchem N-(2-Chloroethyl)-4-fluorobenzamide | ≥95% | CAS 15258-01-2 | C9H9ClFNO | 250mg
N-(2-Chloroethyl)-4-fluorobenzamide | ≥95% | CAS 15258-01-2 | C9H9ClFNO | 250mg
Medchemexpress LLC ML-184 50mg | 794572-10-4 | 470.63 g/mol | C25H34N4O3S | 50 MG
ML-184 is a selective GPR55 agonist research compound (CAS 794572-10-4) used to probe GPR55-mediated signaling pathways in vitro and in vivo. It activates ERK1/2 phosphorylation, promotes PKCβII translocation, and has been shown to increase neural stem cell proliferation and differentiation.
- Selective GPR55 agonist with an EC50 of about 250 nM.
- Greater than 100-fold selectivity over GPR35, CB1, and CB2.
- Induces ERK1/2 phosphorylation and PKCβII membrane translocation.
- Demonstrated activity in neural stem cell proliferation and differentiation assays.
- Provided as a high-purity solid and as a DMSO solution for biological assays.
Sigma Aldrich Fine Chemicals Biosciences Bis(2-chloroethyl)amine hydrochloride 98% | 821-48-7 | MFCD00012515 | 250G
Bis(2-chloroethyl)amine hydrochloride 98% | Purity: 98% | Mol Wt: 178.49 | 821-48-7 | MFCD00012515 | 250G
Medchemexpress LLC 2-phenylaminoadenosine | 53296-10-9 | MFCD00055119 | 98.0% | 358.35 g/mol | C16H18N6O4 | 5 MG
CV1808 (2-phenylaminoadenosine) is a research-grade, non-selective A2 adenosine receptor agonist used in pharmacology and receptor-binding studies. It shows reported Ki values of 76 nM at the A2A receptor and 1,450 nM at the A3 receptor, has molecular formula C16H18N6O4 and molecular weight 358.35 g/mol, and is supplied as a solid with analytical purity around 98.0% for research use only.
- Non-selective A2 adenosine receptor agonist
- Reported Ki: A2A = 76 nM; A3 = 1,450 nM
- Molecular formula C16H18N6O4; molecular weight 358.35 g/mol
- Analytical purity approximately 98.0%
- Supplied as a solid for laboratory research applications
Medchemexpress LLC Gamcemetinib | 1887069-10-4 | 99.1% | C22H20ClN5O3S | 10MG
Gamcemetinib is a covalent, irreversible inhibitor of MAP kinase-activated protein kinase-2 (MK2) used as a research compound for in vitro and preclinical studies. It is characterized by submicromolar activity in biochemical and cell-based assays and is supplied as a solid or as a DMSO solution for laboratory use.
- Potent, covalent MK2 inhibitor with low-nanomolar to submicromolar activity.
- High purity suitable for research use (≈99.1%).
- Available as multiple solid quantities and as a 10 mM solution in DMSO for convenience.
- Soluble in DMSO; enhanced solubility with warming and sonication.
- Defined storage recommendations for powder and solution to preserve stability.
Medchemexpress LLC Vu0467485 | 1451994-10-7 | 99.3% | 25 MG
VU0467485 (AZ13713945) is a potent, selective, orally bioavailable muscarinic acetylcholine receptor 4 (M4) positive allosteric modulator supplied for research use.
- Potent and selective M4 positive allosteric modulator
- Orally bioavailable in preclinical studies
- High purity suitable for analytical and screening applications
- Available in small milligram-scale packages for research
- Characterized molecular weight and formula for reproducibility
Medchemexpress LLC CDC25B-IN-1 | 2374831-10-2 | 98.1% | 321.37 g/mol | C20H19NO3 | 50MG
CDC25B-IN-1 is a small-molecule research inhibitor of the cell division cycle 25B (CDC25B) phosphatase. It has a reported Ki of approximately 8.5 μM, reduces cell proliferation and colony formation, and increases the proportion of cells in the G2/M phase. The compound is supplied at high reported purity and is available in multiple pack sizes, including mg quantities and as a DMSO solution suitable for biochemical and cell-based assays.
- Potent inhibitor of CDC25B phosphatase with reported Ki ≈ 8.5 μM.
- Inhibits cell proliferation and colony formation in cellular assays.
- Causes accumulation of cells in the G2/M phase.
- Supplied with high reported purity for research use.
- Available in multiple pack sizes and as a DMSO solution for convenience.
eMolecules 1122-69-6 | 2-ETHYL-6-METHYLPYRIDINE | AstaTech | MFCD00023531 | 121.183 | C8H11N | 97.000 | CCc1cccc(C)n1 | 0.25g | 721956956
2-ETHYL-6-METHYLPYRIDINE | AstaTech | 1122-69-6 | MFCD00023531 | 121.183 | C8H11N | 97.000 | CCc1cccc(C)n1 | 0.25g | 721956956
Medchemexpress LLC Bis(2-chloroethyl)amine hydrochloride | 821-48-7 | MFCD00012515 | 98.0% | 178.49 g·mol⁻¹ | C4H10Cl3N | 100g
Bis(2-chloroethyl)amine hydrochloride is a biochemical reagent that can be used as a biological material or organic compound for life science related research
Medchemexpress LLC 2-chloroethyl (2-chloroethyl)phosphonate | 17378-30-2 | MFCD24393365 | >95.0% | 206.99 | C4H9Cl2O3P | 5 MG
2-Chloroethyl (2-chloroethyl)phosphonate is an organophosphorus compound used as an intermediate in organic synthesis. It is a low-molecular-weight phosphonate (C4H9Cl2O3P, MW 206.99) with CAS 17378-30-2, provided with supporting documentation; consult the certificate of analysis for recommended storage and handling.
- Organophosphorus intermediate for organic synthesis.
- Molecular formula C4H9Cl2O3P; molecular weight 206.99.
- CAS number 17378-30-2 for unambiguous identification.
- Purity greater than 95% by HPLC.
- Available in small research quantities, such as 5 mg.
- Supplied with certificate of analysis for storage and handling guidance.
Chemscene ChemScene | 4,7-Dibromoisoquinoline | 250MG | CS-0139734 | 0.97 | 223671-10-1| MFCD13191776 | 286.95
ChemScene | 4,7-Dibromoisoquinoline | 250MG | CS-0139734 | 0.97 | 223671-10-1| MFCD13191776 | 286.95
Aobchem N-(2-Chloroethyl)-4-fluorobenzamide | ≥95% | CAS 15258-01-2 | C9H9ClFNO | 1g
N-(2-Chloroethyl)-4-fluorobenzamide | ≥95% | CAS 15258-01-2 | C9H9ClFNO | 1g
Medchemexpress LLC Ascr#18 | 1355681-10-5 | 5 MG
Ascr#18 is an ascaroside that functions as a hormone in nematodes and is expressed during nematode development. It enhances resistance in various plants such as Arabidopsis, tomato, potato, and barley against viral, bacterial, oomycete, fungal, and nematode infections.
- Functions as a hormone in nematodes
- Expressed during nematode development
- Enhances resistance in various plants (Arabidopsis, tomato, potato, barley)
- Provides resistance against viral, bacterial, oomycete, fungal, and nematode infections
- Improves pathogen resistance and activates defense responses in Arabidopsis (in vitro studies)